• Efficient methods development requires rapid exploration of reaction conditions. Uniform amplification protocols have proved to be a long standing bottleneck, constraining our ability to evaluate individually optimal amplification conditions across samples

• This presentation will share examples of how the icon96 system, with its per-well thermal control and AutoNorm adaptive normalization, enables rapid, high-throughput methods development without the constraints of fixed-cycle PCR

 

AZIZ AL’KHAFAJI, Director, Molecular R&D PI, Methods Development Lab, Genomics Platform, Broad Clinical Labs, Broad Institute of MIT and Harvard, N6