• Same-slide spatial multiomics of paired bladder biopsies identified layered drivers of Nectin-4 ADC resistance
• FGFR3/SMAD/TGF-β activation promoted M2 polarization and IL-12 insufficiency, establishing immunosuppressive niches that spatially excluded activated T cells implying multi-node blockade may be required
GULPREET KAUR, Cofounder & Chief Business Officer, Elucidate Biotechnologies